Quality and safety of drugs are essential for effective therapeutic performance. Impurities can compromise the quality and safety of drugs, and they can arise during various stages of the development, production, storage and even transportation process. Therefore, detecting and measuring the number of impurities with high accuracy in drugs is necessary to ensure the quality and safety of drugs and to reduce the risks associated with taking them. Detecting and measuring impurities in drugs require advanced analytical techniques. The review highpoints a variety of analytical chemistry techniques include spectrophotometric and chromatographic methods in addition to some electrochemistry methods that have been applied for determination of certain drugs such as Ciprofloxacin, Metronidazole, Hydroxychloroquine and Cefotaxime in their pure form, combined form with other drugs, combined form with degradation products, and in biological fluids.

In developing countries, it still suffers from endless problems regarding wastewater treatment and the problem of choosing the appropriate treatment system due to lack of proper technology and weak economy. This study highlights the maturity oxidation pond (stabilization) of small communities as an effective, low-cost and simple post-treatment technique for treating wastewater before discharging into an aquatic ecosystem. The Rashid plant was cited as a treatment plant in the city of Rashid-ElBeheira Governorate - Egypt as a model plant for applying this technology in treatment of wastewater. This work also includes the studying of the relationship between climatic conditions, physicochemical parameters and biomass of microorganisms to evaluate the efficiency of its performance.